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Insulin resistance (IR) is a pathological condition in which cells fail to respond to the normal actions of the hormone insulin. The body produces insulin. When the body produces insulin under conditions of insulin resistance, the cells in the body are resistant to the insulin and are unable to use it as effectively, leading to high blood sugar. Beta cells in the pancreas subsequently increase their production of insulin, further contributing to a high blood insulin level. This often remains undetected and can contribute to a diagnosis of Type 2 diabetes or latent autoimmune diabetes of adults. ==Signs and symptoms== These depend on poorly understood variations in individual biology and consequently may not be found with all people diagnosed with insulin resistance.〔(Insulin resistance )〕 # Brain fogginess and inability to focus # High blood sugar # Intestinal bloating – most intestinal gas is produced from carbohydrates in the diet, mostly those that humans cannot digest and absorb # Sleepiness, especially after meals # Weight gain, fat storage, difficulty losing weight – for most people, excess weight is from high fat storage; the fat in IR is generally stored in and around abdominal organs in both males and females; it is currently suspected that hormones produced in that fat are a precipitating cause of insulin resistance # Increased blood triglyceride levels # Increased blood pressure; many people with hypertension are either diabetic or pre-diabetic and have elevated insulin levels due to insulin resistance; one of insulin's effects is to control arterial wall tension throughout the body # Increased pro-inflammatory cytokines associated with cardiovascular disease # Depression: due to the deranged metabolism resulting from insulin resistance, psychological effects, including depression, are not uncommon # Acanthosis nigricans #Increased hunger 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「insulin resistance」の詳細全文を読む スポンサード リンク
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